When the season begins, you can usually pick out a couple of key players to get you started on your new team.
That is not to say you will always have a clear-cut starting XI, however, and there are certain players who will be difficult to gauge.
The big names to look out for are the likes of Messi, Neymar, Gareth Bale and Radamel Falcao.
They all offer an array of attributes that will help your side thrive.
However, a player is not always a guarantee that you will start on a winning team, especially in the Premier League.
You may need to look elsewhere for a new starting XI and some of the other key players will have a higher turnover rate than others.
Here is a guide to finding the best starting XI to start the season in the top flight.
Read more: The best XI to get your team into the top four?